I stumbled upon a very cool utility called DeskPins which allows you to "pin" an application so that it will stay on top of all other applications regardless if it loses focus like Task Manager does. I use it for quite a few scenarios like having a Hulu TV show in the corner while I code, having notepad up while I cut and paste from various applications, and having a little application timer I wrote pinned to the corner during my presentations. It runs in the tray and you can use Ctrl + F12 to pin the current application window to the desktop. A little red pin shows up on the title bar.